Jobs

There are currently no open positions at the Institute for Auditory Neuroscience.

The Institute for Auditory Neuroscience of the University Medical Center Göttingen (Germany) invites applications for a

PhD-Student Position in Synaptic Neuroscience

Mammalian sound encoding relies on faithful and precise neurotransmission between cochlear inner hair cells (IHC) and afferent spiral ganglion neurons. To master this challenging task, the presynaptic active zones of IHCs are equipped with presynaptic specialisations – due to their morphology termed 'synaptic ribbons' – that facilitate high rates of vesicular release and subsequent replenishment, even during prolonged periods of ongoing stimulation. While the molecular architecture and function of ribbon-type active zones has been an area of intense research, the presynaptic development prior to hearing onset still remains enigmatic. Hence, this project will focus on developmental aspects of presynaptogenesis in auditory hair cells and aims to identify the key molecules, as well as the underlying cellular processes that determine the functional maturation and presynaptic plasticity of this high-throughput synapse.

The successful candidate will use gene manipulation approaches in combination with electrophysiology and cutting edge light-microscopic imaging techniques, e.g. live-cell confocal and stimulated emission-depletion (STED) microscopy, to decipher molecular determinants of presynaptic active zone formation and maturation in acutely dissected or cultured mammalian inner ear preparations.

We are looking for highly motivated applicants with a strong background in neuroscience and/or live-cell imaging; additional experience in molecular biology or programming skills are of advantage. Moreover, the ability to work in an interdisciplinary (i.e. combining molecular, ultrastructural and physiological approaches) and international research team is an essential prerequisite. This position is supported by an Otto-Creutzfeldt fellowship of the Helmut & Elisabeth Uhl Foundation and available for 3+ years. Income will be equivalent to E13 65%.

The Göttingen Campus is a leading Neuroscience Center hosting numerous internationally renowned research institutions. This includes the University and its Medical Center, three Max Planck Institutes, the European Neuroscience Institute, and the German Primate Center. The Institute for Auditory Neuroscience & InnerEarLab offers a stimulating multidisciplinary research and training environment and operates state of the art research infrastructure. Moreover, the institute is tightly integrated in the Campus with research groups hosted also at non-university institutions and runs numerous productive collaborations on Campus such as within the collaborative sensory research center SFB 889 , the Bernstein Center for Computational Neuroscience (BCCN) and the Center for Nanoscale Microscopy and Molecular Physiology of the Brain (CNMPB), as well as beyond the campus.

Please submit your application preferably in one single PDF-document, including cover letter, CV, list of publications, names of possible referees, and relevant certificates to: christian.vogl@med.uni-goettingen.de until October 15th, 2017.

Dr. Christian Vogl
Institute for Auditory Neuroscience and InnerEarLab
University Medical Center Göttingen
Robert-Koch-Str. 40
37075 Göttingen
E-mail: christian.vogl@med.uni-goettingen.de

pdf Click here to download the PDF version.


The Institute for Auditory Neuroscience of the University Medical Center Göttingen (Germany) invites applications for a

PhD Student Position in Synaptic Neuroscience

Synapses undergo striking structural and functional changes during maturation. We want to determine ultrastructural changes in synapse characteristics that arise during the conversion of an immature to a mature synapse. We focus on murine calyceal synapses of the early auditory pathway, which undergo functional changes upon the onset of hearing. We will combine different electron microscopic techniques such as electron tomography, FIB as well as SBF-SEM and high-pressure freezing to investigate the ultrastructural changes underlying the functional changes at these synapses in detail in different age-groups. Applicants are expected to have completed university studies in a life science discipline (MSc or diploma). Very good English skills are expected. A background in neuroscience, experience in computer based image analysis, imaging techniques such as confocal fluorescence microscopy and/or especially transmission electron microscopy is beneficial. While providing intense training on the relevant techniques we encourage growing independence in performing the work.

The project is part of the collaborative research center 1286 “Quantitative Synaptology” and the wider Göttingen Campus, which is a leading neuroscience center in Europe hosting numerous prestigious and internationally renowned neuroscience research institutions. This includes the University, three Max Planck Institutes, the European Neuroscience Institute, and the German Primate Center, as well as further collaborative research programs.

Please submit your application preferably in one single PDF-document, including cover letter, CV, list of publications (if applicable), names of possible referees, and relevant certificates to: Prof. Dr. Carolin Wichmann

Prof. Dr. Carolin Wichmann
Group Leader / Principal Investigator
Molecular architecture of synapses Group
Institute for Auditory Neuroscience
Von-Siebold-Str. 3a
Goettingen, Germany
http://www.auditory-neuroscience.uni-goettingen.de/group_Wichmann.html




The Synaptic Nanophysiology Group at MPI for Biophysical Chemistry invites applications for a

PhD Student Position in Synaptic Biophysics

The successful candidate will conduct experimental research on the molecular anatomy and physiology of synaptic transmission at the endbulb and calyx of Held synapses of the auditory pathway. Using state of the art electrophysiology (pre- and/or postsynaptic patch-clamp, capacitance measurements) and optical methods (uncaging, confocal, 2-photon, and STED imaging) in combination with genetically manipulated animals, the project targets fundamental questions in synaptic transmission, such as:

How is the tight coupling of Ca2+-influx and exocytosis at the presynaptic active zone achieved on a molecular level?

What are the molecular mechanisms mediating efficient replenishment of synaptic vesicles to the presynaptic active zone?

We are looking for excellent and highly motivated applicants with a strong background (first degree) in physics, biology, or neuroscience and, ideally, experience in biophysical techniques. Competence in electrophysiology and state of the art light microscopy will be useful. Good computational skills and the ability to work in an interdisciplinary (combining molecular, structural, physiological, and theoretical approaches) and international team of researchers are required. Prior knowledge in theoretical neuroscience is welcome.

The project is part of the collaborative research center 1286 “Quantitative Synaptology” and the wider Göttingen Campus, which is a leading neuroscience center in Europe hosting numerous prestigious and internationally renowned neuroscience research institutions. This includes the University, three Max Planck Institutes, the European Neuroscience Institute, and the German Primate Center, as well as further collaborative research programs.

Please submit your application preferably in one single PDF-document, including cover letter, CV, list of publications (if applicable), names of possible referees, and relevant certificates to: ianoff@gwdg.de

Prof. Dr. Tobias Moser
Professor of Auditory Neuroscience
Synaptic Nanophysiology Group
Max-Planck-Institute for Biophysical Chemistry
Am Fassberg 11
Goettingen, Germany
www.mpibpc.mpg.de/14722384/moser




The German Primate Center GmbH – Leibniz-Institute for Primate Research in Göttingen is a primate research and competence center that does basic research. It concentrates on three main areas named Organismic Primate Biology, Infections Research and Neurosciences. The DPZ maintains three field stations to do research on and with primates. Furthermore it is one of 92 research and infrastructure establishments of the Leibniz Association.
We are offering a full-time position for a

Computer Scientist/Electronics Engineer


as a software and hardware developer in our Auditory Neuroscience workgroup. The contract will initially be for two years but a continuation is intended. Part-time employment is possible.

We are looking for someone who is enthusiastic, versatile and creative. Unrestricted teamwork and a high degree of flexibility are indispensable prerequisites. For the position, a degree as a computer scientist or as an electronics engineer is a requirement.

Your field of work includes the independent development of new hardware and software for novel (optical) cochlear implants in close cooperation with engineering and biomedical scientists. You are required to have extensive experience with microcontrollers i.e. programming, integration and communication with digital signal processing and audio coding, as well as with A/D- und D/A-converters. The command of a higher programming language (preferably C/C++) and assembler is a prerequisite. Experience with MATLAB programming and the knowledge of analog and digital technology are welcome.

Experience with cochlear implants is advantageous since the fitting of optical cochlear implants on animals is planned in cooperation with biomedical scientists. Since the group is international, a command of the English language is a prerequisite.

The appointment at the DPZ follows the applied regulations of civil service. The classification follows the TV-L. In case of equal qualifications disabled persons are preferred.

Please send in your written application including all certificates until the 15.03.2017 under the key word “Auditory Neuroscience” to

Deutsches Primatenzentrum GmbH – Leibniz Institut für Primatenforschung
Personnel Office
Kellnerweg 4
37077 Göttingen

or via mail to bewerbung@dpz.eu.

Further information can be found on our internet pages: http://www.dpz.eu or by calling +49 551 3851-105

pdf Click here to download the PDF version.




Das Institut für Auditorische Neurowissenschaften der Universitätsmedizin Göttingen sucht im Rahmen des Dualen Studiums (BSc / MSc) an der Hochschule für angewandte Wissenschaft und Kunst (HAWK) eine(n)

Elektrotechnikerin/Elektrotechniker bzw. Elektroingenieurin/Elektroingenieur


als Hard- und Software-Entwickler zur sofortigen Besetzung mit einer durchschnittlichen wöchentlichen Arbeitszeit von 20 Std./Woche in einem wissenschaftlichen Projekt ergänzend zum gleichzeitigen Studium. Wir suchen eine vielseitige, kreative und auf hohe Qualität der Arbeit bedachte Persönlichkeit. Uneingeschränkte Teamfähigkeit und hohe Flexibilität sind unverzichtbare Voraussetzungen. Für die Einstellung muss eine abgeschlossene Ausbildung als Elektrotechniker/in oder ein Studienabschluss als Elektroingenieur/in vorliegen.

Ihr Aufgabengebiet umfasst die überwiegend selbständige Entwicklung neuer Hard- und Software für innovative Hörforschung und neuartige (optische) Cochleaimplantate, die Reparatur von vorhandener Hardware sowie die technische Betreuung von physiologischen und psychophysischen Versuchen jeweils in enger Absprache mit Wissenschaftlern und in Kooperation mit den Mitarbeitern der feinmechanischen Werkstatt. Für die Einstellung erforderlich sind Erfahrungen mit Mikrocontrollern, A/D- und D/A-Wandlern (Erfahrung mit National Instruments PC-Boards sind wünschenswert) und digitaler Signalverarbeitung. Neben fundierten Kenntnissen in Analog- und Digitaltechnik ist die Beherrschung einer höheren Programmiersprache (bevorzugt C++) und Assembler gewünscht. Erfahrungen in MATLAB-Programmierung sowie in einer Software zum Herstellen von Platinen-Layouts (bevorzugt Eagle) sind wünschenswert. Durch die internationale Arbeitsgruppe sind Englischkenntnisse notwendig.

Ihre schriftliche Bewerbung sollte Ihren Lebenslauf und ein Motivationsschreiben enthalten.

Senden Sie Ihre Bewerbung, vorzugsweise in elektronischer Form als pdf, an:

Prof. Tobias Moser
Direktor, Institut für Auditorische Neurowissenschaften
37099 Göttingen
Tel.: 0551 / 39-3922803
Fax.: 0551 / 39-3912950
email: ianoff@gwdg.de




Im Institut für Auditorische Neurowissenschaften ist zum nächstmöglichen Termin im Verwaltungsdienst des Sonderforschungsbereichs (SFB) 889 "Zelluläre Mechanismen sensorischer Verarbeitung" folgende Stelle zu besetzen:

Administrativer Koordinator (w/m)


- Entgelt nach TV-L (zunächst bis zum 31.12.2018, Vollzeit, 38,5 Std./Wo.) -

Zu den Aufgaben gehören die Unterstützung bei der Administration des SFB 889 „Zelluläre Mechanismen sensorischer Verarbeitung“ inklusive Mittelverwaltung, Beschaffungen, Vorbereitung von Personalmaßnahmen sowie von Vortrags- und Kursveranstaltungen, Unterstützung von Gastwissenschaftler-Aufenthalten, Unterstützung bei der Erstellung von Berichten und Anträgen sowie der Pflege des Webauftritts des SFB889. Weitere Tätigkeiten sind die Mitorganisation der Aktivitäten des sensorischen Schwerpunkts der Universität Göttingen und die Mitbetreuung des „Sensory and Motor Neuroscience“ Promotionsprogramms der Graduiertenschule GGNB. Gute englische Sprachkenntnisse in Wort und Schrift sind für die Arbeit erforderlich.
SAP-Grundkenntnisse und Kenntnisse in der Drittmittelverwaltung wären wünschenswert.

Die Stelle ist zunächst bis zum 31.12.2018 befristet gem. der aktuellen Förderperiode des SFB 889. Bei Verlängerung des SFB 889 kann die Befristung entsprechend der neuen Laufzeit (voraussichtlich bis 2022) angepasst werden.

Die Universitätsmedizin Göttingen strebt in den Bereichen, in denen Männer unterrepräsentiert sind, eine Erhöhung des Männeranteils an und fordert daher qualifizierte Männer ausdrücklich zur Bewerbung auf. Schwerbehinderte Bewerberinnen/Bewerber werden bei gleicher Eignung bevorzugt berücksichtigt.

Ihre Bewerbung richten Sie bitte bis zum 01.05.2016 an:

Universitätsmedizin Göttingen
Institut für Auditorische Neurowissenschaften
Herrn Prof. Tobias Moser
Institutsleiter, Sprecher des SFB 889
37099 Göttingen
Tel.: 0551/39-22803
Fax: 0551/39-22299
E-Mail: ianoff@gwdg.de

Ihr Ansprechpartner
Dr. Jakob Neef, Tel.: 0551/39-8970

Fahrt- und Bewerbungskosten können nicht erstattet oder übernommen werden.

Bitte reichen Sie Ihre Bewerbungsunterlagen ausschließlich per E-Mail im PDF-Format ein.

Druckversion Stellenanzeige


The developing research cluster "life at the nanoscale" (life@nano) at the University of Göttingen is looking to fill the position of a

Research Associate (PostDoc) - in Nanophysiology

Limited contract of 3 years, full position | Pay grade 13 TV-L


The life@nano fellows are expected to build an independent research program targeting cellular nanoscale machineries. Supported by a modest start-up and affiliated with one or two group(s) of the life@nano consortium, the fellows can take advantage of the scientific infrastructure and environment to tackle fundamental research at the interface of the natural and biomedical sciences.
This position should be filled by the beginning of 2016. The regular working hours will be full time (100%) with a limited contract of 3 years. The position is funded by the State of Lower Saxony. Salary: Pay grade 13 TV-L.
The objective of the research cluster life@nano is to target the structure, function, and dysfunction of non-covalent assemblies with a defined function in a cell, so-called nanoscopic functional units. The life@nano cluster focusses on three main areas: i) supramolecular complexes in gene expression, ii) lipid membrane-based nanodomains for recognition, adhesion, and signalling, and iii) protein-based nanoscopic functional units mediating trafficking processes.
The life@nano initiative involves research groups from Biology, Chemistry, Mathematics, Medicine, and Physics and is a joint initiative of the University of Göttingen, the University Medical Center, the MPI for Biophysical Chemistry, the MPI for Dynamics and Self-Organization, the MPI of Experimental Medicine, the Laser Laboratorium, and the German Center for Neurodegenerative Diseases.
Successful candidates hold a Master and a Ph.D. or equivalent in the natural or biomedical sciences with an excellent track record in high- and superresolution imaging and/or electrophysiology of cellular nanoscopic functional units and should target one of the three main areas given above. They should have demonstrated their ability for interdisciplinary collaboration and should work alongside with life scientists, physicists, mathematicians, and/or chemists on campus.
The University of Göttingen is an equal opportunities employer and places particular emphasis on fostering career opportunities for women. Qualified women are therefore strongly encouraged to apply as they are underrepresented in this field. Disabled persons with equivalent aptitude will be favoured.
Please send your application with the usual documents as well as a short research proposal (not exceeding 5 pages) in electronic form as one single pdf file by January 10th 2016 to the address below.
If you have any questions, please contact Dr. Jakob Neef (phone: +49 551 39 8970, e-mail: jneef@gwdg.de).

Please send your application until January 10th, 2016, to:

Universitätsmedizin Göttingen
Institut für Auditorische Neurowissenschaften
Jakob Neef
Research Coordinator
37099 Göttingen

Tel.: 0551-39-8970
Fax: 0551-39-22299
E-mail: ianoff@gwdg.de
Web: http://grc.uni-goettingen.de/index.php?id=matter

Travel and application fees can not be refunded or transferred.

pdf Click here to download the PDF version.


Das Institut für Auditorische Neurowissenschaft der Universitätsmedizin Göttingen sucht eine/n

Technische Assistentin / technischen Assistenten (MTA/BTA/CTA)

[befristet, Vollzeit] | Entgelt nach TV-L

Über uns
Die Universitätsmedizin Göttingen ist ein Klinikum der Maximalversorgung und bietet vielfältige Entwicklungsmöglichkeiten. 7.000 Mitarbeiterinnen und Mitarbeiter in über 60 Abteilungen und Einrichtungen arbeiten für eine qualitativ hochwertige Patientenversorgung, exzellente Forschung und moderne Lehre. Als Stadt der Wissenschaft liegt Göttingen im Zentrum Deutschlands, die Universitätsmedizin Göttingen ist eingebunden in ein attraktives Netzwerk wissenschaftlicher Forschungseinrichtungen.
Das Institut für Auditorische Neurowissenschaft beschäftigt sich mit der molekularen Anatomie, Physiologie und Pathophysiologie der synaptischen Informationsverarbeitung im Hörsystem sowie mit deren Wiederherstellung mit modernsten molekulargenetischen Methoden.
Im Rahmen des EU-geförderten Projektes „OptoHear“ entwickeln wir neuartige Verfahren zur optogenetischen Wiederherstellung des Hörvermögens. Wir suchen eine motivierte, teamfähige Persönlichkeit, um das Team im Bereich der molekular- und zellbiologischen Aufgaben zu verstärken.

Zu Ihren Aufgaben gehören
• Klonierung von Kanalrhodopsinsequenzen und Herstellung von viralen AAV-Vektoren
• Expressionsanalyse in Zellkultur
• Erstellung immunhistochemischer Präparate
• Die selbstständige Organisation und Dokumentation der experimentellen Arbeiten
• Herstellung von Puffern und Lösungen
• Genotypisierungen

Was Sie mitbringen
• Erfolgreich abgeschlossene Berufsausbildung als MTA, BTA oder CTA (oder vergleichbare Ausbildung)
• Molekularbiologische Kenntnisse
• Ggf. Berufserfahrung im Bereich der Herstellung viraler Vektoren
• Gute MS-Office- und Englischkenntnisse setzen wir voraus

Schwerbehinderte Bewerberinnen/Bewerber werden bei gleicher Eignung bevorzugt berücksichtigt.

Wir freuen uns auf Ihre Bewerbung bis zum zum 30.11.15, vorzugsweise in elektronischer Form (einzelnes pdf-Dokument), an:

Prof. Tobias Moser
Direktor, Institut für Auditorische Neurowissenschaften
37099 Göttingen
Tel.: 0551 / 39-3922803
Fax.: 0551 / 39-3912950
email: ianoff@gwdg.deWeb: http://www.auditory-neuroscience.uni-goettingen.de


The Institute for Auditory Neuroscience and InnerEarLab of the University Medical Center Göttingen (Germany) invites applications for a

Postdoctoral Position in Synaptic Nanophysiology

The successful candidate will conduct biophysical experiments and modeling on the synaptic nanoanatomy and nanophysiology targeting experimentally well accessible synapses of the auditory pathway. Our work aims at elucidating the presynaptic mechanisms of exocytosis, endocytosis, Ca2+ influx-exocytosis and -endocytosis coupling, active zone clearance and vesicle replenishment. We target the large active zones of inner hair cell ribbon synapses and the large calyceal endbulb of Held synapses. We use state of the art electrophysiology (pre- and/or postsynaptic patch-clamp, capacitance measurements) and optical methods (uncaging, confocal, 2-photon and STED imaging) to study normal and genetically manipulated synapses, and combine the experiments with biophysical modelling to target fundamental research questions such as: How is the high temporal precision of the auditory code brought about by a chain of stochastic events at the hair cell synapse?

We are looking for excellent and highly motivated applicants with a strong background in physics or biology and proven experience in biophysical techniques. Competence in electrophysiology and state of the art microscopical imaging will be useful. Good computational skills and the ability to work in an interdisciplinary (combining molecular, structural, physiological and theoretical approaches) and international team of researchers are required. Prior knowledge in theoretical neuroscience is welcome.

The Göttingen Campus is a leading Neuroscience Center hosting numerous prestigious and internationally renowned research institutions. This includes the University and its Medical Center, three lifescience Max Planck Institutes, the European Neuroscience Institute and the German Primate Center. The Institute for Auditory Neuroscience & InnerEarLab is tightly integrated in the Campus with research groups hosted also Non-University Institutions and runs numerous stimulating collaborations on Campus such as within the collaborative sensory research center SFB889 (www.sfb889.uni-goettingen.de/), the Bernstein Center for Computational Neuroscience (BCCN, www.bccn-goettingen.de) and the Center for for Nanoscale Microscopy and Molecular Physiology of the Brain (www.cmpb.uni-goettingen.de).

Please submit your application preferably in one single PDF-document, including cover letter, CV, list of publications, names of possible referees, and relevant certificates to: ianoff@gwdg.de until March 31st 2015

pdf Click here to download the PDF version.


The Institute for Auditory Neuroscience and InnerEarLab of the University Medical Center Göttingen (Germany) invites applications for a

Postdoctoral position in molecular biology of the auditory system

The successful candidate will work on genetic manipulation of auditory hair cells and neurons using viral and non-viral transduction and mouse mutagenesis. The focus of the work is on the molecular physiology of sound coding, gene therapy approaches, and the use of optogenetics to restore auditory activity in auditory neurons. The work involves cloning, packaging, and testing of constructs/virus in cell culture, organotypic culture, and in vivo (transuterine or postnatal gene transfer into the inner ear). Phenotyping is done as a team effort using state of the art electrophysiology (pre- and/or postsynaptic patch-clamp, capacitance measurements) and optical methods (uncaging, confocal, 2-photon and STED imaging, optogenetics, electron microscopy) and provides ample opportunities to learn new methods. 

We are looking for excellent and highly motivated applicants with a strong background in molecular biology/genetics. Competence in virus production (AAV) will be useful. The ability to work in an interdisciplinary (combining molecular, structural, physiological, and theoretical approaches) and international team of researchers is required. The position is available for 5 years.

The Göttingen Campus is a leading Neuroscience Center hosting numerous prestigious and internationally renowned research institutions. This includes the University and its Medical Center, three lifescience Max Planck Institutes, the European Neuroscience Institute, and the German Primate Center. The Institute for Auditory Neuroscience & InnerEarLab is tightly integrated in the Campus with research groups hosted also non-University institutions and runs numerous stimulating collaborations on Campus such as within the collaborative sensory research center SFB889 (www.sfb889.uni-goettingen.de), the Bernstein Center for Computational Neuroscience (www.bccn-goettingen.de), and the Center for Nanoscale Microscopy and Molecular Physiology of the Brain (www.cnmpb.de).

Please submit your application preferably in one single PDF-document, including cover letter, CV, list of publications, names of possible referees, and relevant certificates to: ianoff@gwdg.de until February 28th 2015.

pdf Click here to download the PDF version.