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Die Arbeitsgruppe Molekulares und Zelluläres Opsin Engineering des Instituts für auditorische Neurowissenschaft sowie des Else-Kröner-Fresenius-Zentrums für optogenetische Therapien und sucht eine*n

Biologisch-technische*n Assistent*in (w/m/d)

- Vollzeit (38,5 h/Woche) mit der Option auf Teilzeit, vorerst befristet für zwei Jahre und der Möglichkeit auf Verlängerung, Entgelt nach TV-L -

Die Arbeitsgruppe Molekulares und Zelluläres Opsin Engineering beschäftigt sich mit der Charakterisierung und Entwicklung neuer lichtsensitiver Schalter für die neurobiologische Grundlagenforschung und optogenetische Therapie neurodegenerativer und neurosensorischer Erkrankungen. Im Mittelpunkt unserer Forschung stehen sowohl der Mechanismus lichtempfindlicher Proteine, meist Opsine, als auch deren optogenetische Anwendung in enger interdisziplinärer Zusammenarbeit mit anderen Forschungsgruppen des Instituts und des Zentrums.

Zur Unterstützung unserer zell- und molekularbiologischen Arbeiten suchen wir eine motivierte und teamfähige Verstärkung für unser Labor.

Ihre Aufgaben:

  • Labormanagement: eigenverantwortliche Labororganisation, Beschaffung von Verbrauchsmaterialien und Betreuung von Laborgeräten
  • Betreuung der Zellkultur, einschließlich der Kultivierung permanenter Zelllinien im S1-Labor sowie deren Vorbereitung für elektrophysiologische Experimente und molekulare Bildgebung.
  • Durchführung molekularbiologischer Arbeiten> (Herstellung kompetenter Zellen, Klonierung und Modifikation heterologer Expressionsvektoren)
  • Expression und Aufreinigung von Photorezeptorproteinen
  • Unterstützung der funktionalen Charakterisierung von Photorezeptoren mittels Fluoreszenz- und Biolumineszenzassays
  • Dokumentation und Optimierung von Versuchsprotokollen sowie Einarbeitung neuer Mitarbeiter*innen
  • Perspektivisch die Präparation primärer neuronaler Zellkulturen aus dem Hippocampus der Maus

Ihr Profil:

  • Berufsausbildung mit staatl. Anerkennung (BTA, MTA, CTA, MTLA oder vergleichbare Qualifikation)
  • Erfahrungen mit tierischen Zelllinien und Zellkulturen
  • Kenntnisse auf dem Gebiet der Molekularbiologie (Klonierung, gerichtete Mutagenese, Herstellung kompetenter Zellen)
  • Grundlegende Kenntnisse in computergestützter Datenanalyse und -darstellung (z.B. Excel, Word, PowerPoint)
  • Selbstständige, engagierte und zuverlässige Arbeitsweise, Teamfähigkeit sowie Interesse und Freude an biologischen Fragestellungen

Weiterhin von Vorteil wären:

  • Erfahrungen mit heterologer Proteinexpression und Aufreinigung
  • Kenntnisse der Licht- und Fluoreszenzmikroskopie
  • Bereitschaft zur Arbeit mit Mausmodellen und Erfahrungen mit primären Zellkulturen.
  • Gute Englischkenntnisse für die Arbeit in einem internationalen Team

Wir bieten:

  • Eine anspruchsvolle und vielseitige Tätigkeit in einem jungen und engagierten Team sowie die Möglichkeit, den Aufbau und die Weiterentwicklung einer neuen Forschungsgruppe aktiv mitzugestalten.
  • Individuelle Fort- und Weiterbildungsmöglichkeiten
  • Vergütung nach TV-L mit verschiedenen Sozialleistungen, z.B. betrieblicher Altersversorgung

Der Göttingen Campus ist ein führendes Zentrum der Neurowissenschaften mit zahlreichen international renommierten Forschungseinrichtungen, darunter Universität und die Universitätsmedizin Göttingen, zwei naturwissenschaftliche Max-Planck-Institute, das European Neuroscience Institute, das Deutsche Primatenzentrum sowie – seit Neustem - auch das Else-Kröner-Fresenius-Zentrum für optogenetische Therapien.

Ihre Bewerbung richten Sie bitte über das UMG-Jobportal bis zum 30.09.2026 an

Universitätsmedizin Göttingen
Else-Kröner-Fresenius Zentrum für optogenetische Therapien
Institut für Auditorische Neurowissenschaften
Prof. Dr. Johannes Vierock
37077 Göttingen

Tel.: +49-551-38-51193

E-Mail: Johannes.vierock@med.uni-goettingen.de

Web: https://www.auditory-neuroscience.uni-goettingen.de/group_Vierock.html

Wir bitten Sie um Verständnis, dass Fahrt- und Bewerbungskosten nicht erstattet werden können.

Bitte reichen Sie Ihre Bewerbungsunterlagen im PDF-Format in einer Datei ein.

link Klicken Sie hier um sich über das JobPortal der UMG zu bewerben.

pdf Klicken Sie hier, um die Stellenanzeige als PDF herunterzuladen.


The Molecular and Cellular Opsin Engineering Lab at the Institute for Auditory Neuroscience and the Else-Kröner-Fresenius-Center for Optogenetic Therapies is offering a

PhD Student Position (m/f/d) – New Opsins for Optogenetic Therapies

- starting as soon as possible, initially limited to three years with the option to extend, salary according to 65% TV-L E13 -

We are looking for a highly motivated PhD student with a background in biophysics, biochemistry, molecular biology or neuroscience and a strong interest in protein engineering and optogenetics to advance our efforts in the engineering of light-gated ion channels and the development of a new generation of optogenetic actuators for therapeutic applications.

The Molecular and Cellular Opsin Engineering Lab has recently moved to Göttingen and is part of the highly interdisciplinary and collaborative research environment of the Institute for Auditory Neuroscience and the Else Kröner-Fresenius Center for Optogenetic Therapies. The Center brings together biochemists, neuroscientists, engineers, and medical researchers from different disciplines with the shared goal of advancing optogenetic technologies toward clinical applications.

Göttingen is an internationally renowned center for neuroscience and biomedical research. The Georg-August University and University Medical Center Göttingen, the Max Planck Institute for Multidisciplinary Sciences, the European Neuroscience Institute, and the German Primate Center provide an exceptionally strong and internationally connected research environment. PhD students can additionally benefit from the interdisciplinary training and networking opportunities offered by the Göttingen Graduate Center for Neurosciences, Biophysics, and Molecular Biosciences (GGNB).

Your tasks:

  • Molecular cloning, genetic modification, and expression of new opsins in mammalian cell cultures and primary neurons
  • Functional characterization of new opsins using molecular biology, biochemical assays, fluorescence microscopy, live-cell imaging, and whole-cell patch-clamp electrophysiology
  • Development and optimization of experimental workflows for higher-throughput screening, including automated data analysis where applicable
  • Design of new optogenetic tools and subcellular targeting strategies, together with the development of new experimental approaches
  • Regular presentation of your work in lab meetings, thesis advisory committee meetings, and scientific conferences, and contribution to collaborative scientific publications in international peer-reviewed journals
  • Opportunity to gain experience in supervising Bachelor’s and Master’s students

Your profile:

  • We are looking for an open-minded, enthusiastic, and highly motivated junior researcher with strong analytical and interpersonal skills, the ability to think independently and a demonstrable interest in basic biological research questions.
  • Completed Master’s degree or equivalent in biology, biophysics, physics, biochemistry, molecular medicine, neuroscience, or a related discipline
  • Practical laboratory experience and basic knowledge of working with biological samples
  • Experience with quantitative data analysis and scientific presentation
  • Proficient communication and writing skills in English
  • Previous experience in one or more of the following areas would be advantageous but is not required: molecular biology, electrophysiology, live-cell imaging, automated data analysis, or work with photoreceptors and light-sensitive samples. Training in complementary techniques will be provided.

We offer:

  • A 65% position according to TV-L E13, initially funded for three years, with a possibility for extension
  • A highly collaborative and interdisciplinary research environment with excellent scientific networking opportunities, structured supervision through a thesis advisory committee, and comprehensive scientific training and career-development opportunities
  • Access to state-of-the-art infrastructure for molecular biology, imaging, electrophysiology, and optogenetic research
  • The opportunity to join a newly established and growing research group, combining the advantages of a small lab — close scientific supervision, direct mentoring, and the freedom to shape your research questions and experimental strategies — with the excellent infrastructure and collaborative environment of a leading international research institution

The position is available immediately, with a flexible starting date, and we encourage interested candidates to apply as soon as possible.

Your application should include:

  • A detailed curriculum vitae
  • A cover letter describing your research interests and motivation
  • Contact details for at least two referees

Please send your application directly to Prof. Dr. Johannes Vierock at Johannes.vierock@med.uni-goettingen.de.

…and do not hesitate to contact us if you have any questions.

We are looking forward to your application!

pdf Click here to download the job description as a PDF.


The Institute for Auditory Neuroscience of the University Medical Center Göttingen (Germany) invites applications for a

Postdoc position (f/m/d)

- starting as soon as possible, full time, initially limited until 31.12.2028, salary according to TV-L -

Your tasks:

  • In-depth structural and functional characterization of optimized Channelrhodopsin variants for basic research in neuroscience and future optogenetic therapies
  • Recombinant protein purification, Determination of protein stability (Prometheus NT. 48, NanoTemper Technologies), SDS PAGE, Blue Native PAGE
  • Cryo-EM (Titan Krios G4, Thermo Fisher Scientific)
  • High-throughput spinning disc confocal microscopy (CQ1, Yokogawa)
  • Data analysis

Your profile:

  • Excellent and highly motivated applicant with a strong background in the structural and functional characterization of membrane transport proteins
  • Proficiency in structural biology and preferably knowledge in bioinformatics and/or patch clamp measurements and/or data-driven protein design
  • Experience with basic molecular biology techniques (PCR, cloning etc.)
  • Preferably knowledge in the characterization of microbial rhodopsins
  • Basic skills in data analysis with Python
  • Excellent organizational, interpersonal and communication skills
  • The ability to work in an interdisciplinary and international team of researchers is required

We offer:

  • Exciting work and collaboration in a multi-disciplinary team
  • A highly innovative project
  • The chance to contribute to work towards the development of future optogenetic therapies, in particular the optical cochlear implant

The Göttingen Campus is hosting numerous prestigious and internationally renowned research institutions. This includes the University and its Medical Center, two life science Max Planck Institutes, the European Neuroscience Institute, and the German Primate Center. The Institute for Auditory Neuroscience & InnerEarLab is tightly integrated in the Campus with research groups hosted also at non-university institutions and runs numerous stimulating collaborations on Campus such as within the collaborative research center CRC 1690 (Disease Mechanisms and Functional Restoration of Sensory and Motor Systems) and the newly founded Else Kröner Fresenius Center for Optogenetic Therapies (EKFZ-OT).

We are looking forward to your application!

pdf Click here to download the job description as a PDF.

link Click here to apply via UMG's JobBoard.


The Else Kröner Fresenius Center for Optogenetic Therapies invites applications for a

Software-/Electronics Engineer (f/m/d)

for the development of hardware and software

- initially limited until 31.10.2028 with possibility of extension, full time, salary according to TV-L -

The EKFZ-OT of the University Medical Center Göttingen is dedicated to the translation of the four core optogenetic approaches to restore i) hearing and ii) vision and to explore the potential of optogenetics for iii) gastric pacemaking and iv) brain-computer interfaces. These four teams are supported by technology platforms for 1) opsin engineering, 2) gene transfer, 3) disease models, 4) immune- phenotyping and 5) development of medical devices.

The EKFZ-OT builds on a close interdisciplinary collaboration between scientists of the University Medical Center Göttingen, the departments of Physics, Mathematics, and Biology of the University, and non- university research institutions in Göttingen, such as the German Primate Center and the Max Planck Institutes for Multidisciplinary Sciences and for Dynamics and Self-Organization, as well as partners at the Medical University Hannover (MHH), University of Freiburg and Technical University of Chemnitz.

Your tasks:

  • Development of new hardware and software for innovative medical devices such as optical cochlear implants, including wireless power transmission, FPGA, and ASIC design.

Your profile:

  • Bachelor’s degree or higher in computer science, electrical engineering, or a related field
  • At least 2 years of experience with embedded systems
  • Knowledge of the IEC 62304 standard
  • Experience with PCB layout design (preferably using Eagle or KiCad)
  • Experience with microcontrollers, FPGAs, and antenna design
  • Experience with digital signal processing
  • Experience with MATLAB/Python is desirable
  • Fluency in English is required due to the international nature of the work environment; knowledge of German is a plus

We offer:

  • A challenging and varied job within a committed and motivated team
  • Opportunities to develop your individual strengths and skills through our comprehensive training and professional development programs
  • Salary according to TV-L with various social benefits, e.g. a company pension scheme

Our goal as University Medical Center Göttingen is professional equality for all genders. We strive to achieve a balanced gender ratio in areas where there is underrepresentation. The University Medical Center Göttingen is particularly committed to the professional participation of disabled persons and therefore welcomes applications from disabled persons. In case of equal suitability, applications from disabled persons will be given preferential consideration in accordance with the relevant regulations. We kindly ask you to indicate any disability/equal status in your letter of application.

Please submit your application with cover letter, CV, references and certificates by August 31st, 2026 exclusively via the UMG online application portal (https://umg.recruiting-portal.com/r/z00g8fkp0f59abj/Software-Elektronik-Ingenieur+mwd/37075/G%C3%B6ttingen) and address it to:

University Medical Center Göttingen
Institute for Auditory Neuroscience
Prof. Dr. Tobias Moser, Director
37099 Göttingen

Tel.: 0551/39-63071

We ask for your understanding that travel and application costs cannot be reimbursed.

pdf Click here, to download the job posting as a PDF file.

link Click here, to apply via UMG's JobBoard.


The Institute for Auditory Neuroscience of the University Medical Center Göttingen (Germany) invites applications for a

PhD student position (f/m/d) in Structural and Molecular Biology

- starting as soon as possible, initially limited until 31.12.2028, salary according to TV-L -

The position is embedded in the newly founded Collaborative Research Center (CRC) 1690 “Disease Mechanisms and Functional Restoration of Sensory and Motor Systems”, and the successful candidate will contribute to the project “Dissecting the mechanisms of otoferlin-driven synaptic vesicle fusion at inner hair cell ribbon synapses”.

We’re looking for a motivated researcher to join a cutting-edge project exploring how otoferlin, a key protein in hearing, drives rapid and precise neurotransmitter release in inner hair cells. You’ll use advanced structural biology techniques—like cryo-EM and AI-driven modeling—to study otoferlin’s dynamic interactions with membranes, SNARE proteins, and other fusion machinery. Your work will involve reconstituting protein complexes, analyzing their structure and function, and testing new ideas about how otoferlin might directly trigger vesicle fusion. This is a unique opportunity to tackle a fundamental question in neuroscience with real implications for understanding deafness and developing future therapies.

Göttingen is world renowned for its research in neuroscience. It is a stimulating and highly collaborative scientific environment hosting numerous prestigious and internationally renowned neuroscience research institutions. This includes the University and its Medical Center, lifescience Max Planck Institutes, the European Neuroscience Institute and the German Primate Center. The InnerEarLab, which includes several research groups of the Institute for Auditory Neuroscience and Dept. of Otolaryngology and outside University, is tightly integrated in the Campus, where it runs numerous stimulating collaborations such as within CRC1690 and the Multiscale Bioimaging Cluster of Excellence. Most PhD students are enrolled in the competitive „Sensory and Motor Neuroscience“ program of the Göttingen Graduate School for Neurosciences, Biophysics, and Molecular Biosciences (GGNB), which offers attractive interdisciplinary training platform and networking for PhD students.

Your tasks:

  • Express, purify and assemble multimeric protein complexes for structural studies (e.g., using the MultiBac and MultiMam systems)
  • Biochemically characterize protein complexes, prepare, and image cryo-EM samples
  • Establish cryo-EM image analysis pipelines for reconstituted complexes, and build, refine, and validate structural models
  • Establish otoferlin-based vesicle fusion assays (coupled lipid and context mixing)
  • Validate structural models using site-directed mutagenesis and functional assays
  • Present your progress in regular thesis advisory committee meetings, lab meetings, scientific meetings, and research conferences
  • Contribute to joint scientific publications
  • Participate in a doctoral qualification program well suited to the research focus of the CRC

Your profile:

  • Master’s degree or equivalent in biochemistry, molecular biology, chemistry, or a related discipline, ideally with previous research experience in structural biology or biochemistry (cryo-EM/cryo-ET, X-ray crystallography, or NMR) or in protein engineering and purification for functional studies
  • Extensive experience working with sensitive multimeric protein complexes and/or large membrane proteins is highly desirable
  • Familiarity with cryo-EM/cryo-ET or X-ray crystallography data processing, model building and refinement (using RELION, cryoSPARC, Warp, Phenix, Coot) is highly desirable
  • Experience with relevant biochemical methodologies (bulk vesicle fusion assays, liposome or nanodisc reconstitution, FRET-based assays), AI-based image analysis, knowledge of sensory neuroscience, and computational skills (Linux, Python, R, bash) are advantageous
  • Skills in data analysis with Python
  • The ability to work in an interdisciplinary, English-speaking team of researchers is required

We offer:

  • Attractive employee compensation and benefit package according to the standards of the German public sector
  • A research- and qualification program in line with the CRC´s scientific mission
  • Clinically relevant research with strong links to patient care
  • Working with a highly engaged and interdisciplinary team of scientists at the Institute for Auditory Neuroscience, one of the world leading institutions in inner ear research
  • Highly collaborative research environment with excellent scientific networking possibilities
  • State-of-the-art research infrastructure
  • Structured and multi-layered supervision by a thesis advisory committee
  • A comprehensive career development support program

We’re looking forward to your application!

pdf Click here to download the PDF version of this job advert.

link Click here to apply via UMG's recruitment system.


The Collaborative Research Center 1690 is offering two

Clinician Scientist positions (f/m/d)

- full time, 12-18 months of funding -

The Collaborative Research Center (CRC) 1690 is a research center of the University of Göttingen and the University Medical Center Göttingen and pursues a multidisciplinary and integrative approach to elucidate disease mechanisms in sensory and motor systems and to work towards their functional restoration. We target the mechanisms underlying genetic, age-related, and immune-related disorders of the inner ear and the retina and extend to general principles of neural dysfunction. Working towards translation of results from basic research into clinical application, we develop innovative approaches for functional restoration of diseased sensory and motor systems and utilize new insights into the function and dysfunction of those systems as well as novel technological opportunities. We pursue preclinical studies on optogenetic restoration of auditory, visual, somatosensory, and laryngeal function and on inner ear regeneration, and we develop smart control strategies for sensory and motor prostheses. In this context, we offer two clinician scientist positions for medical staff interested in working in a scientific setting. Applicants should please send their current CV along with a short (~2 page) outline of their research proposal along with their motivation letter.

Your tasks:
Clinician Scientists are given the opportunity to plan and realize their own research project. The project needs to be within the scientific scope of the CRC 1690 "Disease Mechanisms and Functional Restoration of Sensory and Motor Function", be supervised by a principal investigator of the CRC and a clinical mentor, and should be affiliated with one of the CRC's projects.

Your qualifications:

  • Completed studies in human medicine with license to practice medicine
  • Medical doctorate, at least completed experimental part of the doctoral thesis or research experience for several months
  • Proof of scientific interest by a scientifically sound and promising project outline
  • Independent, responsible, flexible working style and ability to work in an international team
  • We offer:

  • Participation in translational research in sensory and motor neuroscience
  • A broad spectrum of research topics
  • Close transdisciplinary collaboration between teams working on different topics with a common interest
  • Support of the own research project by the host laboratory through supervision, research infrastructure, and provision of funding for consumables
  • If you are interested, please contact sfb1690@med.uni-goettingen.de for more information.

    link Click here to apply via UMG's recruitment system.


    The Institute for Auditory Neuroscience of the University Medical Centre Göttingen is offering a new position for the earliest start date

    PhD student position (f/m/d) in Auditory Systems Physiology

    - full time, till end of 2028, possible extension, remuneration according to TV-L -

    The position is embedded in the newly founded Collaborative Research Center (CRC) 1690 “Disease Mechanisms and Functional Restoration of Sensory and Motor Systems”. In our project, we study the disease mechanisms of human hearing loss. Based on our cooperative clinical work in otolaryngology and human genetics, we have identified three novel deafness gene candidates, and we continue to seek for more. We will characterize the expression and function of these genes in the murine cochlea.

    We try to understand how different forms of hearing impairment affect sound encoding. Our special interest is on auditory synaptopathy/neuropathy, where the sensory inner hair cells and their ribbon synapses do not function normally. We use genetically modified mice to better understand the role of deafness genes in hearing function. With a direct connection between the lab work in mice and state of the art clinical testing in audiology, our aim is to better understand normal and impaired hearing function and to improve diagnostic techniques and hearing rehabilitation strategies. We are also interested in the interaction between genetic alterations causing hearing impairment and the susceptibility to noise trauma.

    Göttingen is world renowned for its research in neuroscience. It is a stimulating and highly collaborative scientific environment hosting numerous prestigious and internationally renowned neuroscience research institutions. This includes the University and its Medical Center, lifescience Max Planck Institutes, the European Neuroscience Institute and the German Primate Center. The InnerEarLab, which includes several research groups of the Institute for Auditory Neuroscience and Dept. of Otolaryngology and outside University, is tightly integrated in the Campus, where it runs numerous stimulating collaborations such as within CRC 1690 and the Multiscale Bioimaging Cluster of Excellence. Most PhD students are enrolled in the competitive „Sensory and Motor Neuroscience“ program of the Göttingen Graduate School for Neurosciences, Biophysics, and Molecular Biosciences (GGNB), which offers attractive interdisciplinary training platform and networking for PhD students.

    Your tasks:

  • Analyze the expression of putative novel deafness genes and interacting proteins by immunohistochemistry (confocal and STED microscopy), RNAscope, qPCR, and Western Blots
  • Assess hearing function in genetically modified mice using in vivo recordings from the rodent auditory system (auditory brainstem responses, otoacoustic emissions, potentially also electrocochleography, endocochlear potential measurements, single unit recordings from the auditory nerve, behavioral assessments of hearing function)
  • Perform other in vitro electrophysiology or cell culture work
  • Present your progress in regular thesis advisory committee meetings, lab meetings, scientific meetings, and research conferences
  • Contribute to joint scientific publications
  • Participate in a doctoral qualification program well suited to the research focus of the CRC
  • Your qualifications:

  • Master’s degree or equivalent in neuroscience, audiology, physiology, animal biology or molecular medicine, ideally with a focus on sensory physiology
  • Previous experience in relevant research methodology and technology and basic knowledge regarding sensory neuroscience is appreciated, especially regarding electrophysiological experiments, microsurgery, immunohistochemical staining procedures and / or confocal or STED imaging. Knowledge of image analysis as well as technical and programming skills (ideally in Matlab) are appreciated. A completed course on animal experimentation (FELASA B) will be useful
  • Completed course on animal experimentation (FELASA B), and basic programming skills (e.g. in Matlab) would be helpful
  • The ability to work in an interdisciplinary, collaborative, English-speaking international team of researchers is required
  • We offer:

  • Attractive employee compensation and benefit package according to the standards of the German public sector (position available till end of 2028, with possible extension)
  • A research- and qualification program in line with the CRC´s scientific mission
  • Working with a highly engaged and interdisciplinary team of scientists at the Institute for Auditory Neuroscience, one of the world leading institutions in inner ear research
  • Highly collaborative research environment with excellent scientific networking possibilities
  • State-of-the-art research infrastructure
  • Structured and multi-layered supervision by a thesis advisory committee
  • A comprehensive career development support program
  • link Click here to apply via UMG's recruitment system.


    The Klinik für Hals-Nasen-Ohrenheilkunde of the University Medical Center Göttingen is looking for a new position for the earliest start date

    PhD student position (f/m/d) in Experimental Otology

    - full time, till end of 2028, possible extension, remuneration according to TV-L -

    CRC1690 is a newly founded DFG-funded collaborative research center investigating disease mechanisms of sensory and motor disorders and developing novel therapeutic approaches towards sensory and motor restoration.

    Hearing impairment is the most common sensory disorder in humans, with more than 700 million people projected to be affected by 2050. Eighty percent of prelingual hearing loss is attributed to genetic causes, and can adversely impact speech, language development, and education. In adults, hearing impairment may lead to social isolation, depression and cognitive decline. The PhD project addressed hereditary hearing impairment linked to malfunction of the voltage-gated calcium channels that critically mediate hair cell synaptic transmission. The successful candidate will work on elucidating the regulation of these channels and developing and optimizing gene therapeutic approaches in mouse disease models to prepare for putative future causative treatment in the patients. Work will employ genetic tools, manual and automated patch-clamp measurements, immunohistochemistry, confocal/STED imaging, light-sheet fluorescence microscopy, and systems physiology tests.

    Göttingen is world renowned for its research in neuroscience. It is a stimulating and highly collaborative scientific environment hosting numerous prestigious and internationally renowned neuroscience research institutions. This includes the University and its Medical Center, lifescience Max Planck Institutes, the European Neuroscience Institute and the German Primate Center. The InnerEarLab, which includes several research groups of the Institute for Auditory Neuroscience and Dept. of Otolaryngology and outside University, is tightly integrated in the Campus, where it runs numerous stimulating collaborations such as within the collaborative sensory research center SFB1690, and the Multiscale Bioimaging Cluster of Excellence. Most PhD students are enroled in the competitive „Sensory and Motor Neuroscience“ program of the Göttingen Graduate School for Neurosciences, Biophysics, and Molecular Biosciences (GGNB) which offers attractive interdisciplinary training platform and networking for PhD students.

    Your tasks:

  • Study the disease mechanism of hearing loss caused by defects in voltage-gated calcium channel function/regulation in mouse models
  • Develop preclinical gene therapeutic approach to treat hearing impairment, related to calcium channels
  • Perform experiments spanning manual and automated patch-clamp measurements, immunohistochemistry with confocal/STED imaging, light-sheet fluorescence microscopy, and systems physiology hearing tests; report, summarize, share and analyze data
  • Present your progress in regular thesis advisory committee meetings, lab meetings, scientific meetings and research conferences
  • Contribute to joint scientific publications
  • Participate in a doctoral qualification program well suited to the research focus of the CRC
  • Your qualifications:

  • Master’s Degree in Biomedical Sciences, Animal Biology, Neuroscience, Audiology, Physiology, or Molecular medicine or equivalent from an accredited institution
  • Previous experience in relevant research methodology and technology and basic knowledge in hearing appreciated
  • Completed course on animal experimentation (FELASA B), and basic programming skills (e.g. in Matlab) would be helpful
  • The ability to work in an interdisciplinary, collaborative, English-speaking international team of researchers is required
  • We offer:

  • Attractive employee compensation and benefit package according to the standards of the German public sector (position available till end of 2028, with possible extension)
  • A research- and qualification program in line with the CRC´s scientific mission
  • Working with a highly engaged and interdisciplinary team of scientists in the field at the Department of Otolaryngology and Institute for Auditory Neuroscience
  • Highly collaborative research environment with excellent scientific networking possibilities
  • State-of-the-art research infrastructure
  • Structured and multi-layered supervision by a thesis advisory committee
  • A comprehensive career development support program
  • pdf Click here to download the PDF version of this job advert.

    link Click here to apply via UMG's recruitment system.


    We welcome applications for PhD collaboration. We are looking for excellent and highly motivated applicants with a strong background (first degree) in biology, (biomedical) engineering, physics, or neuroscience.
    Competence in electrophysiology, behavioral approaches, state of the art light microscopy, and/or computational data analysis will be useful. If interested, please send your application to one of the group leaders or to ianoff@gwdg.de.