Our publications on optogenetic hearing restoration

If you can't obtain access to one of the publications, please contact the authors.



2021

bioRxiv, 2021 May 25th
Fast photoswitchable molecular prosthetics control neuronal activity in the cochlea
Garrido-Charles A, Huet A T, Matera C, Thirumalai A, Llebraria A, Moser T, Gorostiza P

EMBO Molecular Medicine, 2021 May 7th EMBO Mol Med (2021)e13391, https://doi.org/10.15252/emmm.202013391
Utility of red-light ultrafast optogenetic stimulation of the auditory pathway
Bali B, Lopez de la Morena D, Mittring A, Mager T, Rankovic V, Huet AT, Moser T

PNAS, 2021 May 4th, 118 (18) e2014472118; https://doi.org/10.1073/pnas.2014472118
Multiscale photonic imaging of the native and implanted cochlea
Keppeler D, Kampshoff C, Thirumalai A, Duque-Afonso CJ, Schaeper J, Quilitz T, Töpperwien M, Vogl C, Hessler R, Meyer A, Salditt T, Moser T

Frontiers in Molecular Neuroscience, 2021 March 11th, https://doi.org/10.3389/fnmol.2021.635897
Developing fast, red-light optogenetic stimulation of spiral ganglion neurons for future optical cochlear implants
Huet AT, Dombrowski T, Rankovic V, Thirumalai A, Moser T



2020

Nature Communications 2020 Nov 11;11(1):5707. doi: 10.1038/s41467-020-19457-7
Viral rhodopsins 1 are an unique family of light-gated cation channels
Zabelski D, Alekseev A, Kovalev K, Rankovic V, Balandin T, Soloviov D, Bratanov D, Saveljeva E, Podolyak E, Vokov D, Vaganova S, Astashkin R, Chizov I, Yutin N, Rulev M, Popov A, Eria-Oliveria A-S, Rokitskay T, Mager T, Antonenko Y, Rosselli R, Armeev G, Shaitan K, Vivaudou M, Büldt G, Rogachev A, Rodriguez-Valera F, Kripchnikov M, Moser T, Offenhäuser A, Willbold D, Koonin E, Bamberg E, Gordeliy V

Methods in Molecular Biology 2021, 2020 Sep 01;2191:261-285. doi: 10.1007/978-1-0716-0830-2_16
Application of targeting-optimized Chronos for stimulation of the auditory pathway
Huet A, Rankovic V

Science Translational Medicine, 2020 Jul 22;Vol. 12, Issue 553, eabb8086. DOI: 10.1126/scitranslmed.abb8086
Multichannel optogenetic stimulation of the auditory pathway using microfabricated LED cochlear implants in rodents
Keppeler D, Schwaerzle M, Harczos T, Jablonski L, Dieter A, Wolf B, Ayub S, Vogl C, Wrobel C, Hoch G, Abdellatif K, Jeschke M, Rankovic V, Paul O, Ruther P, Moser T
[abstract] [reprint] [full text]

EMBO Molecular Medicine, 2020 Jun 29;e12387. doi: 10.15252
μLED-based optical cochlear implants for spectrally selective activation of the auditory nerve
Dieter A, Klein E, Keppeler D, Jablonski L, Harczos T, Hoch G, Rankovic V, Paul O, Jeschke M, Ruther P, Moser T

bioRxiv, May 2020, preprint
Hearing restoration by a low-weight power-efficient multichannel optogenetic cochlear implant system
Jablonski L, Harczos T, Wolf B, Hoch G, Dieter A, Hessler R, Ayub S, Ruther P, Moser T

Physiological Reviews, 2020 Jul 6, 100(4):1467-1525. doi: 10.1152/physrev.00035.2019
Emerging approaches for restoration of hearing and vision
Kleinlogel S, Vogl C, Jeschke M, Neef J, Moser T

EMBO Molecular Medicine, 2020 Mar 30. e11618, doi.10.15252/emmm.201911618
Towards the Optical Cochlear Implant: Optogenetic Approaches for Hearing Restoration
Dieter A, Keppeler D, Moser T

Biochemical and Biophysical Research Communications, 2020 Feb 4. pii: S0006-291X(20)30090-5. doi: 10.1016/j.bbrc.2019.12.126
Towards optogenetic approaches for hearing restoration
Moser T, Dieter A



2019

Nature Communications, 2019 Apr 29, 10 1962, doi: 10.1038/s41467-019-09980-7
Near physiological spectral selectivity of cochlear optogenetics
Dieter A, Duque Afonso CJ, Rankovic V, Jeschke M, Moser T



2018

EMBO Journal, 05 Nov 2018, doi: 10.15252/embj.201899649
Ultrafast optogenetic stimulation of the auditory pathway by targeting-optimized Chronos
Keppeler D, Martins Merino R, Lopez de la Morena D, Bali B, Huet AT, Gehrt A, Wrobel C, Subramanian S, Dombrowski T, Wolf F, Rankovic V, Neef A, Moser T

Cold Spring Harbor Laboratory Press, October 15th, 2018, a033225 doi: 10.1101/cshperspect.a033225
Toward the optical cochlear implant
Dombrowski T, Rankovic V, Moser T

Science Translational Medicine 11 Jul 2018: Vol. 10, Issue 449, eaao0540 DOI: 10.1126/scitranslmed.aao0540
Optogenetic stimulation of cochlear neurons activates the auditory pathway and restores auditory-driven behavior in deaf adult gerbils
Wrobel C, Dieter A, Huet A, Keppeler D, Duque-Afonso CJ, Vogl C, Hoch G, Jeschke M, Moser T

Nature Communications 2018 May 1 doi:10.1038/s41467-018-04146-3
High frequency neural spiking and auditory signaling by ultrafast red-shifted optogenetics
Mager T, Lopez de la Morena D, Senn V, Schlotte J, D´Errico A, Feldbauer K, Wrobel C, Jung S, Bodensiek K, Rankovic V, Browne L, Huet A, Jüttner J, Wood P, Letzkus J, Moser T, Bamberg E

Scientific Reports 8 March 21, 2018.
Propagation-based phase-contrast x-ray tomography of cochlea using a compact synchrotron source
Töpperwien M, Gradl R, Keppeler D, Vassholz M, Meyer A, Hessler R, Achterhold K, Gleich B, Dierolf M, Pfeiffer F, Moser T, Salditt T



2014 - 2017

Curr Opin Neurobiol. 2015 Jan 28;34C:29-36. doi:10.1016/j.conb.2015.01.004. Review.
Optogenetic stimulation of the auditory pathway for research and future prosthetics.
Moser T.

Hear Res. 2015 Jan 16. pii: S0378-5955(15)00008-8. doi:10.1016/j.heares.2015.01.005. Review.
Considering optogenetic stimulation for cochlear implants.
Jeschke M, Moser T.

J Vis Exp. 2014 Oct 8;(92):e52069. doi: 10.3791/52069.
Optogenetic stimulation of the auditory nerve.
Hernandez VH, Gehrt A, Jing Z, Hoch G, Jeschke M, Strenzke N, Moser T.

J Clin Invest. 2014 Mar 3;124(3):1114-29. doi:10.1172/JCI69050.
Optogenetic stimulation of the auditory pathway.
Hernandez VH, Gehrt A, Reuter K, Jing Z, Jeschke M, Mendoza Schulz A, Hoch G, Bartels M, Vogt G, Garnham CW, Yawo H, Fukazawa Y, Augustine GJ, Bamberg E, Kügler S, Salditt T, de Hoz L, Strenzke N, Moser T.